Quan-Plex™ Molecular CytoPath Reference Slides - In collaboration with multinational clinical research laboratories AccuRef Diagnostics has developed the Quan-Plex™ Molecular CytoPath Reference Slide Panel – a validated, multigene cytopathology panel, that is the first and only reference standard panel to mimic fine needle aspirates (FNAs). The panel consists of three mutations in the MAPK pathway that are dPCR-validated allelic frequencies of 0% (wild-type), 1%, 5%, 10%. These slides are ideal for proficiency testing or clinical laboratory workflow training, thus saving precious clinical specimens for final assay validation.
Price: $475.00
Datasheet
Gene | Nucleotide | Amino Acid | Cosmic | Frequency |
---|---|---|---|---|
EGFR | c.2369C>T | p.T790M | COSM6240 | 0%, 1%, 5%, 10% |
KRAS | 38G>A | G13D | COSM532 | 0%, 1%, 5%, 10% |
EGFR | 2235_2249del15 | E746_A750delELREA | COSM6223 | 0%, 1%, 5%, 10% |
Catalog | ARF-1002F | |||||||||
Size | 1 slide panel | |||||||||
Format | Methanol fixed - Kwik-Diff™ resistant | |||||||||
Volume/Dimension | 1" X 0.5" cell smear | |||||||||
Quantity | 4 slides (10%, 5%,1% and 0% MAF) | |||||||||
Concentration | ~200,000 cells/ slide (typically ~ 50 ng gDNA/slide) | |||||||||
Cell(s) | RKO | |||||||||
Shelf Life | 12 months | |||||||||
Buffer | Tris-EDTA (10 mM Tris-HCl, 1 mM EDTA), pH 8.2 | |||||||||
Shipping Temperature | Ambient | |||||||||
Fixation Process | methanol fixation: 70%, 4 hours at room temperature | |||||||||
Storage Temperature | -20°C | |||||||||
Quality Control | Genotype: Sanger sequencing of locus-specific PCR (cell line) Quality: Kwik-Diff™ (uniformity of cell distribution) Quantification: Cell counter Mutation Allelic Frequency: Digital PCR Manufacturing: ISO 9001:2015 and ISO 13485:2016 Certified | |||||||||
Freeze/Thaw | No more than 3 cycles | |||||||||
Regulatory | Research Use Only. Not Intended for human or animal diagnostic or therapeutic use. | |||||||||
Restrictions | This is a limited use product. This product, any material that contains this product in whole or in part, any progeny, modification or derivative of this product, any cell or animal made or modified by using this product, and any progeny, modification or derivative of such cell or animal may not be transferred by the purchaser to any other person, entity or any of the above to perform services for the benefit of any other person or entity or for commercial purpose of any kind. This product may only be used by the purchaser for its internal research for use as a research tool for research purposes. |